Each Pioreactor has built-in heating <i>and</i> temperature sensors. I emphasize temperature sensors, since I've used enough hot plates to not trust a graduated knob to have any reliability. With a combination of heating and temperature sensors, the Pioreactor is able to keep a set temperature for the culture, regardless of the Pioreactor variations in the construction, ambient temperature, etc.
One of our goals with the Pioreactor is design it such that you don't need to be a biologist, or an electrical engineer, or relevant for this article: a statistician. This article describes our internal algorithm that computes the culture's growth rate, but importantly: you don't need to know this algorithm to use the Pioreactor! We've designed the internal statistical algorithm to be robust enough that you can sit back and watch. This article is for the users who really want to dig deep into how we compute growth rates and the statistics behind it.
This week we investigated some sampling tricks to improve our ADCs, and managed to get a 50% reduction in signal variance, and gain many more bits in our signal, using data science!